Figure 10 - full size

 

Figure 10.
Figure 10. Reaction mechanism based on a model where the substrate has been positioned in the active site so as to overlap with the analogous parts of the inhibitor. Figure 10. Reaction mechanism based on a model where the substrate has been positioned in the active site so as to overlap with the analogous parts of the inhibitor.

The above figure is reprinted by permission from Cell Press: Structure (1994, 2, 937-944) copyright 1994.