Figure 1 - full size

 

Figure 1.
Fig. 1. (A) Structure of the SDF-1 dimer with the secondary structure assignments for monomer 1 based on the program INSIGHTII (Biosym Technologies, San Diego) shows the extended N-terminal loop proceeding into the single turn of a 3[10] helix and strands 1, 2, and 3 followed by the C-terminal helix packing almost orthogonally to the three-stranded antiparallel -sheet. (B) The IL-8 dimer is shown to highlight the differences between the IL-8 and SDF-1 dimers.