|
Figure 1.
Figure 1. Schematic representation of the biosynthesis of
purine nucleotides in S. cerevisiae. For each step, the name of
the enzyme and the structural gene (in parentheses) are given.
The reaction catalysed by SAICAR synthase is shown in red.
Abbreviations: AICAR, phosphoribosylaminoimidazolecarboxamide;
AIR, phosphoribosylaminoimidazole; CAIR,
phosphoribosylcarboxyaminoimidazole; FAICAR,
phosphoribosylformylaminoimidazolecarboxamide; FGAM,
phosphoribosylformylglycinamidine; FGAR,
phosphoribosylformylglycinamide; GAR, phosphoribosylglycinamide;
PR, 5-phosphoribosyl; PRA, phosphoribosylamine; PRPP,
5-phosphoribosyl 1-pyrophosphate.
|
