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Figure 1.
Solution structure of CzrO DNA-bound CzrA. (A) Backbone heavy
atom (N, Cα, and C') overlay of 20 lowest-energy structures of
DNA bound CzrA (see Table S2 for structure statistics;
unstructured residues 100–103 of the bundle are not shown in
this view for clarity). The ribbon diagram in the overlay
represents the mean structure of the ensemble and the two
subunits are shaded salmon and red. (B) Ribbon diagram
representation of the global overlay of DNA bound CzrA and the
crystal structure of Zn(II) CzrA (8). The subunits of DNA bound
CzrA are colored as in A and the two subunits of Zn(II) CzrA are
colored slate and blue. Zn(II) ions are colored yellow. (C)
Another view of the same overlay as in B (rotated 45°) and
the green arrows represent the direction of the quaternary
structural change.
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