Figure 1 - full size

 

Figure 1.
Fig. 1. Chemical formulas of inhibitors 1 to 6 discussed in this study. Inhibitory potency towards human thrombin is given as kinetic inhibition constant K[i] with the SD from averaging of at least three measurements. Relative differences of the thermodynamic properties between inhibitors, as indicated by the arrows, are given in kilojoules per mole.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2009, 391, 552-564) copyright 2009.