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Figure 1.
Fig. 1. Stereoview images of the wild-type (teal) and
Sa(F98Y) mutant (gold) enzymes bound to: a, compound 5
(wild-type light green, F98Y cyan); b, compound 8 (wild-type
orange, F98Y lavender); c, compound 10 (wild-type purple, F98Y
dark green); and d, compound 15 (wild-type yellow, F98Y gray).
The standard conformation of NADPH is shown in magenta and the
alternative conformation is shown in blue. Water molecules
(shown in Fig. 3) are omitted for clarity.
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