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Figure 1.
Comparison of the structures of the RF1 and RF2 termination
complexes. (A) RF2 termination complex (this work), showing RF2
(yellow), P-site tRNA (orange), E-site tRNA (red), mRNA (green),
16S rRNA (cyan), 23S and 5S rRNA (gray), 30S proteins (blue),
and 50S proteins (magenta). (B) RF1 termination complex (9);
molecular components are colored similarly as in A. (C) RF2 in
its ribosome-bound conformation, rotated ≈180° from the
view shown in A, with domains numbered. The GGQ and SPF motifs
are shown in red, and the switch loop is shown in orange. (D)
RF1 in its ribosome-bound conformation. The GGQ and PVT motifs
are indicated in red and the switch loop is shown in orange.
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