Figure 1 - full size

 

Figure 1.
Figure 1: GLIC structure. a, Ribbon representation of GLIC viewed from the plane of the membrane. DDM molecules bound in the channel are depicted as yellow sticks plus van der Waals surface. Horizontal lines represent the membrane limits. b, Transmembrane part of GLIC viewed from the extracellular side. The ECD is removed for clarity. Lipids are also depicted in orange. c, Topology of a GLIC subunit. The conserved core elements common to GLIC and ELIC are coloured in yellow. d, Close-up view of the TMD. Only two subunits are represented. The DDM molecules and the lipids (named LIP601/2/3) close to these subunits are coloured according to their atomic B-factor (colour scale at top).

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2009, 457, 111-114) copyright 2009.