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Figure 1.
Structure of EXLX1 and comparison with other proteins
containing a double-ψ β-barrel fold and interacting with
polysaccharides. (A) Diagram representation of EXLX1: D1, cyan;
D2, magenta. (B) Diagram representations of EXLX1 and EXPB1
(orange) superimposed. (C) Diagram representations of EXLX1 and
EcMltA(D308A)–chitohexaose superimposed. The chitohexaose
[(GlcNAc)[6]] is shown as sticks. Nt, N-terminal extension. (D)
Diagram representations of GH45 endoglucanase MeCel45A and EXPB1
superimposed. (E) Diagram and surface representation of EXLX1
with chitohexaose (in sticks) from the superimposed
EcMltA(D308A)–chitohexahose. The most conserved residues in
proteins with a double-ψ β-barrel fold are highlighted in
yellow. EXLX1 is oriented with shallow groove on the front
instead of on top as in A–D.
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