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Figure 1.
Figure 1. Structural Comparison of BAR Domain and BAR
Domain-Related Proteins
(A–F) Crystal structures of (A)
Snx9^PX-BAR (Pylypenko et al., 2007; this study) and of the (B)
BAR-PH module of APPL1 (PDB: 2ELB) ([Li et al., 2007] and [Zhu
et al., 2007]) are shown in two orthogonal views in their
dimeric state. Dimeric crystal structures of isolated N-BAR
domains from (C) Endophilin (PDB: 1X03) (Masuda et al., 2006)
and (D) Amphiphysin (PDB: 1URU) (Peter et al., 2004), the (E)
F-BAR domain from CIP4 (PDB: 3EFK) (Shimada et al., 2007), and
the (F) I-BAR domain of IRSp53 (PDB: 1Y2O) (Millard et al.,
2005) are shown. The degree of curvature of BAR domain dimers is
indicated as gray lines.
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