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Figure 1.
Figure 1: Reactions catalysed by the CYP74 enzyme family. In
higher plants, C[18] fatty acids (linoleic and linolenic acids)
are oxygenated at either position 9 or 13 by lipoxygenases to
yield hydroperoxides. Subsequently, these are converted by
allene oxide synthase (AOS, also known as CYP74A), hydroperoxide
lyase (HPL, also known as CYP74B) and divinyl ether synthase
(DES, also known as CYP74D) to allene oxide (an essential
intermediate in jasmonate biosynthesis), green leaf volatiles
(aldehydes) and divinyl ethers, respectively. For clarity, only
13-hydroperoxide-derived metabolites are shown. 12,13(S)-allene
oxide, 12,13S-epoxy-9Z,11,15Z-octadecatrienoic acid; 13(S)-HPOT,
13S-hydroperoxyoctadecatrienoic acid;  -ketol
is the hydrolytic product of the highly unstable allene oxide;
hemiacetal, hydroxyhexenyloxydodecadienoic acid.
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