Figure 1.
FIGURE 1. Biosynthesis of PEB and PCB. PEB biosynthesis
proceeds via two different pathways. PebA and PebB catalyze
consecutive two-electron reductions of BV and 15,16-DHBV to
yield PEB. PebS catalyzes the four-electron reduction of BV to
PEB via the two-electron reduced intermediate 15,16-DHBV. PcyA
catalyzes a four-electron reduction of biliverdin IX to PCB
via the intermediate 18^1,18^2-DHBV. The electrons for all
reactions come from reduced [2Fe-2S] ferredoxin (Fd[red]). The
carbons of the respective reduction sites are numbered. Fd[ox],
oxidized ferredoxin; P, propionate side chain.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2008,
283,
27547-27554)
copyright 2008.
to PCB
via the intermediate 18^1,18^2-DHBV. The electrons for all
reactions come from reduced [2Fe-2S] ferredoxin (Fd[red]). The
carbons of the respective reduction sites are numbered. Fd[ox],
oxidized ferredoxin; P, propionate side chain.