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Figure 1.
Figure 1: Structure of the second CA repeat of CDCA1 (CDCA1-R2).
a, Overall structure of the Cd-bound CDCA1-R2. Two lobes of
the structure are coloured blue and green. Cd is highlighted in
red, and Cd-coordinating residues are coloured yellow. b,
Comparison of the active site conformation between CDCA-R2
(green) and 
-CA (blue). The active site residues in CDCA-R2 and -CA
are coloured yellow and orange, respectively. Hydrogen bonds are
represented by red dashed lines. Cd and the water ligand are
shown in large and small red spheres, respectively. (A stereo
view is shown in Supplementary Fig. 1b.) c, Comparison of Cd-
and Zn-coordination in CDCA1-R2. Metal coordination and hydrogen
bonds are indicated by red and green dashed lines, respectively;
numbers indicate bond lengths in Å. W1–W3, water
molecules. Structural images were prepared using MOLSCRIPT^44
and GRASP^45.
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