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Figure 1.
Figure 1. Biochemical Analysis of RIG-I Variants
(A)
RIG-I and MDA5 variants used in this study.
(B) Catalytic
efficiency (k[cat] K[m]^−1) of WT RIG-I and ΔCARD-RIG-I,
RIG-I-ΔRD and the DECH domain for pppRVL (black bars), and
nonphosphorylated dsRNA (white bars). Error bars represent
standard errors of the nonlinear regression analysis
(Supplemental Data).
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