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Figure 1.
Figure 1. Structure of human CLIC2. (A) Structure based
sequence alignment of human CLIC1-6 and DHAR2, DHAR3 from A.
thaliana. Identical and conserved residues are colored in red
and yellow, respectively. CXXC motif is colored in cyan and
marked by upwards triangles. The additional N-terminal sequences
of CLIC5 and CLIC6 were truncated. (B) Overall structure of
CLIC2. N-terminal domain is colored in red; C-terminal domain in
green, the joint
loop in
yellow, the foot
loop in
blue, disulfide bond between Cys^30 and Cys^33 is showed as
stick (yellow). (C) Structure superimposition of CLIC1 (yellow),
CLIC4 (red) structures on CLIC2 (green). Disulfide bond in CLIC2
is showed in stick (yellow).
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