Figure 1 - full size

 

Figure 1.
Figure 1. Structure of human CLIC2. (A) Structure based sequence alignment of human CLIC1-6 and DHAR2, DHAR3 from A. thaliana. Identical and conserved residues are colored in red and yellow, respectively. CXXC motif is colored in cyan and marked by upwards triangles. The additional N-terminal sequences of CLIC5 and CLIC6 were truncated. (B) Overall structure of CLIC2. N-terminal domain is colored in red; C-terminal domain in green, the joint loop in yellow, the foot loop in blue, disulfide bond between Cys^30 and Cys^33 is showed as stick (yellow). (C) Structure superimposition of CLIC1 (yellow), CLIC4 (red) structures on CLIC2 (green). Disulfide bond in CLIC2 is showed in stick (yellow).

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2008, 71, 509-513) copyright 2008.