Figure 1 - full size

 

Figure 1.
FIGURE 1. A, primary structure alignment of Hu-TTR and Mu-TTR. Stars at the bottom indicate identical amino acid residues. B, two views of the crystal structure of Mu-TTR superimposed on that of Hu-TTR. Each mouse TTR subunit is shown in a different color; Hu-TTR is shown in gray. Dashed lines indicate the dimer interfaces, and the crystallographic C[2] x axis is labeled.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2008, 283, 2098-2107) copyright 2008.