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Figure 1.
Fig. 1. Structure of PapR5:PlcR and comparison to
cCF10:PrgX. Shown are ribbon presentations of PapR5:PlcR (A) and
cCF10:PrgX (B) [Protein Data Bank entry 2AXZ (9)]. Chains A and
B of PlcR and PrgX are colored in magenta and cyan, with their
respective HTH domains in dark gray and dark blue. Helix 3 of
the HTH domains that inserts into the major DNA groove is
colored in red. The C-terminal extension of PrgX is colored in
light gray. Ligand peptides are shown in yellow and green. Left
and Right represent 90° views. (C and D) Close-up views of
the peptide–protein interactions for PapR:PlcR (C) and
cCF10:PrgX (D). Oligopeptides are yellow, and key residues are
labeled. Unbiased 3F[o]–2F[c] electron density for PapR5 is
shown in gray. Hydrogen bonds between cCF10 and PrgX key
residues are indicated by black lines.
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