Figure 1 - full size

 

Figure 1.
Figure 1. A diagram of CSQ polymerization. The CSQ molecule exists as either a monomer or a wide range of high molecular mass clusters, depending on the ionic environment. The extended N terminus of CSQ establishes the front-to-front dimer interface through arm exchange. Following a further increase of the concentration of Ca^2+, the carboxy terminus of CSQ, which is the most negative region, forms tetramer and higher-order linear polymers capturing substantial amounts of Ca^2+ in the back-to-back interface.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2007, 373, 1047-1057) copyright 2007.