Figure 1 - full size

 

Figure 1.
Fig. 1. Overall structure of TEP1r. (A) Domain arrangements of TEP1r in comparison with human C3 (PDB ID 2A73). The mature protein commences with domain MG1 (medium blue) followed by MG2 (orange), MG3 (purple), MG4 (medium gray), MG5 (light green), MG6 (pink), LNK (light brown), MG7 (light blue), CUB (navy blue), TED (dark green), MG8 (yellow), and ANK (light gray). Additional domains in C3 are the ANA domain (red, between MG3 and MG8) and the C345C domain (dark red, top). (B) Sequence schematic of TEP1r, showing disposition of domains. (C) The relative position of MG3 to MG7-MG8 in TEP1r compared with human C3.