Figure 1 - full size

 

Figure 1.
Figure 1. Structure of the PDE4D D201N catalytic domain. (a) Ribbons diagram. The large red ball represents a zinc ion. The green sticks are the residues at the active site of the PDE4D2 D201N mutant. (b) Superposition of the active site residues of the wild-type PDE4D2 (blue sticks) over those of the D201N mutant. The zinc ion has the same position in the wild-type and D201N structures. The magnesium ion is from the wild-type PDE4D2.

The above figure is reprinted from an Open Access publication published by Elsevier: J Mol Biol (2007, 371, 302-307) copyright 2007.