Figure 1 - full size

 

Figure 1.
Figure 1. The 2F[o] - F[c] electron density map for the crystal structure of PR[V82A]/SQV. The major conformation is colored by atom type and the minor one is in magenta. (A) Saquinavir (contoured at 2.2 level). (B) Residues 79-82 (contoured at 1.8 level). (C) Catalytic site (contoured at 1.8 level). Asp25 and 25 are shown with the hydroxyl group of SQV.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2007, 67, 232-242) copyright 2007.