Figure 1.
FIGURE 1. Tyr residues participating in the interaction of
HyHEL10 and HEL. a, overall structure of the wild-type HyHEL-10
Fv-HEL complex. C- traces of VL, VH, and
HEL are drawn in green, cyan, and pink, respectively. Tyr
residues contacting HEL are represented by orange sticks.
Interfacial water molecules bridging Fv and HEL are represented
by red balls. b, space-filling model of the wild-type HyHEL-10
Fv fragment from the direction of the antigen-binding site. The
contacting residues in VL and VH are shown in green and cyan,
respectively. Tyr residues are shown in orange. Interfacial
water molecules are shown in red. c, space-filling model of HEL.
The residues contacting the six Tyr residues of HyHEL-10 are
shown in orange, and the other contacting residues are shown in
pink.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2007,
282,
6783-6791)
copyright 2007.
traces of VL, VH, and
HEL are drawn in green, cyan, and pink, respectively. Tyr
residues contacting HEL are represented by orange sticks.
Interfacial water molecules bridging Fv and HEL are represented
by red balls. b, space-filling model of the wild-type HyHEL-10
Fv fragment from the direction of the antigen-binding site. The
contacting residues in VL and VH are shown in green and cyan,
respectively. Tyr residues are shown in orange. Interfacial
water molecules are shown in red. c, space-filling model of HEL.
The residues contacting the six Tyr residues of HyHEL-10 are
shown in orange, and the other contacting residues are shown in
pink.