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Figure 1.
Figure 1: Structures of human CPSF-73 and yeast CPSF-100 (Ydh1).
a, Schematic representation of the structure of human
CPSF-73. The -strands
and -helices
are labelled, and the two zinc atoms in the active site are
shown as grey spheres. The sulphate ion is shown as a stick
model. b, Schematic representation of the structure of yeast
CPSF-100. The zinc atoms in the CPSF-73 structure are shown for
reference. See Supplementary Fig. 2 For Schematic drawings of
the metallo- -lactamase
domains of the two proteins.
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