Figure 1.
FIGURE 1. A F[o] - F[c] electron density map (contoured at
3.5 , purple cage) at the
active site when the side chain of His-11 and the ligand are
omitted. A (structure 1), co-crystallized with 2,3-BPG at 4
°C. B (structure 2), co-crystallized with 2,3-BPG at 16
°C for less than 16 days. C (structure 3), only 3-PGA
binding. D (structure 4), co-crystallized with 2,3-BPG at 16
°C for 17 days. Extra F[o] - F[c] electron density
(contoured at 3 , blue cage) exists
when two water molecules and 3-PGA are modeled in. E (structure
5), co-crystallized with and
3-PGA.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2006,
281,
39642-39648)
copyright 2006.
, purple cage) at the
active site when the side chain of His-11 and the ligand are
omitted. A (structure 1), co-crystallized with 2,3-BPG at 4
°C. B (structure 2), co-crystallized with 2,3-BPG at 16
°C for less than 16 days. C (structure 3), only 3-PGA
binding. D (structure 4), co-crystallized with 2,3-BPG at 16
°C for 17 days. Extra F[o] - F[c] electron density
(contoured at 3 
and
3-PGA.