Figure 1.
Figure 1: Structures of Saccharomyces cerevisiae eEF3 and
nucleotide binding. a, Schematic representation of the
eEF3 sequence. See the text for a description of the different
domains. Chromo, chromodomain; C-term, carboxy-terminal domain.
b, Stereo view of the crystal structure of eEF3–ADP. The
nucleotide is shown in ball-and-stick representation. c, Stereo
view of the nucleotide-binding site. The electron density of ADP
is generated from an omit map contoured at 1.5 (grey)
or at 0.8 around
the -phosphate
(green). d, Three different conformations of eEF3. Left: crystal
structure of eEF3. Middle: ATP model of eEF3 constructed using
homology to the structure of MJ0796. Right: Cryo-electron
microscopy (cryo-EM) reconstruction of eEF3 on the 80S ribosome.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nature
(2006,
443,
663-668)
copyright 2006.
(grey)
or at 0.8 
-phosphate
(green). d, Three different conformations of eEF3. Left: crystal
structure of eEF3. Middle: ATP model of eEF3 constructed using
homology to the structure of MJ0796. Right: Cryo-electron
microscopy (cryo-EM) reconstruction of eEF3 on the 80S ribosome.