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Figure 1.
Figure 1. Structure of ATP-DnaA. (a) Overlay of the four DnaA
monomers in the asymmetric unit. The AAA+ module is colored
green and red (domains IIIA and IIIB, respectively); domain IV,
the DNA-binding element, is yellow. The ATP analog AMP-PCP is
shown as black sticks. The helix-turn-helix (HTH) motif in
domain IV and the N and C termini are labeled. (b) ATP-DnaA
forms a right-handed helical filament with 8[1] symmetry. Side
and axial views of four symmetry-related DnaA tetramers are
shown. Top, the four monomers in the asymmetric unit are colored
blue, green, orange and yellow. Bottom, identical view, but
protomers are colored by domain as in a.
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