Figure 1 - full size

Figure 1. Figure 1 Main figure: ribbon representation of the Pfal008434AAA dimer. The A chain is colored smoothly from blue at the N-terminus to red at the C-terminus. The B chain is colored by domain, with the larger domain in pink and the smaller domain in purple. The tetramerization loop of chain A is indicated by an arrow. Inset: enlarged view of the active site of the Pfal008434AAA A chain. The bound phosphate ion is shown in stick form and the three water molecules mentioned in the text are indicated as spheres. The substrate ribose 5-phosphate (light blue) from the T. thermophilus structure 1uj5 is shown superposed onto the Pfal008434AAA active site based on superposition of 27 C^ atoms in two stretches of chain that contain ten of the 11 residues directly in contact with the ribose 5-phosphate. The figure was generated using PyMOL (DeLano, 2002[DeLano, W. (2002). The PyMOL Molecular Graphics System. http://www.pymol.org .]).

The above figure is reprinted from an Open Access publication published by the IUCr: Acta Crystallograph Sect F Struct Biol Cryst Commun (2006, 62, 427-431) copyright 2006.