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Figure 1.
Figure 1. Organic solvent binding sites. Ribbon diagram of
elastase showing the binding sites for organic solvent molecules
in a common frame of reference. Each site is numbered as
described in the text. The number of the sites occupied by
organic solvent molecules in each of the models is given in
Table 2. The catalytic triad is shown explicitly in the cleft
between the two b-barrel domains: Ser203, His60, Asp108 are
shown in gray. The b-strands are shown in purple and the two
a-helices are shown in green. The organic solvent molecules are
color-coded as follows: HEX, salmon; ETH, hot pink; TFE1, cyan;
TFE2, orange; IPR, light green; IBZ, green; ICY, dark green;
ACE, red; DMF, blue; ACN, yellow. Figure 1, Figure 2, Figure 3
and Figure 4 were made using the program MOLSCRIPT.52
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