Figure 1 - full size

 

Figure 1.
Figure 1. Crystal structure of USP7 NTD bound to p53 site 359-PGGS-362. (a) Transparent surface diagrams of p53–USP7. (b) Detailed interactions between USP7 (light gray) and p53 (dark gray). (c) Overlay of p53 (red) and EBNA1 (green) peptides from complex structures. (d) Overlay of p53 (red) and TRANCE-R (yellow) peptides from complex structures, showing conserved interactions with USP7 (purple) and TRAF6 (blue) residues.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Mol Biol (2006, 13, 285-291) copyright 2006.