Figure 1 - full size

 

Figure 1.
Fig. 1. Structural alignment of SPRK, PRK and VPRK. Helices (red tubes) and sheets (yellow arrows) are according to SPRK. Residues belonging to the S1 site are shaded blue and residues belonging to the S4 site are shaded light blue. *represents residues that are involved both in the S1 and S4 sites. Residues forming the calcium binding site found in SPRK (and VPRK) are shaded green, residues forming the ‘strong’ calcium binding site in PRK (and in VPRK) are shaded khaki, and residues forming the calcium sites unique for either PRK or VPRK are shaded pale green.

The above figure is reprinted by permission from the Federation of European Biochemical Societies: FEBS J (2006, 273, 61-71) copyright 2006.