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Figure 1.
FIGURE 1. Electron density of the bound ligands and overall
fold of Ta LplA. A, 2F[o] - F[c] electron density maps of the
bound ligands. Atoms of the ligands are also labeled. B, ribbon
diagram of Ta LplA. Secondary structure elements were assigned
by PROMOTIF (26).  -Helices,  -strands,
and loops are colored in red, blue, and yellow, respectively.
Lipoyl-AMP bound near the center of LplA is shown in sticks. All
the figures except Fig. 3 are drawn with PyMOL (DeLano, 2002,
The PyMOL Molecular Graphics System, www.pymol.org). C, topology
diagram of Ta LplA. -Strands are shown as
triangles and -helices as circles. D,
stereo C trace of Ta LplA. Every
tenth residue is marked by a black dot, and every twentieth
residue is labeled. Three signature sequence motifs are
highlighted in colored lines: motif I (RRXXGGGXV(F/Y)HD at
positions 71-82) in red, motif II (KhXGXA at positions 145-150)
in green, and motif III (HXX(L/M)LXXX(D/N)LXXLXXhL at positions
161-177) in blue, respectively.
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