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Figure 1.
Figure 1. Pyrimidine nucleotide biosynthesis and the roles of
UMPK demonstrated in Escherichia coli. Prokaryotic UMPK is
highlighted within a grey box. The eukaryotic CMP/UMPK is
included also. Multiple arrows denote multiple steps. The broken
and dotted arrows denote feed-back inhibition and activation,
respectively. The double-lined arrow indicates repression by
UMPK of the carAB genes, which encode carbamoyl phosphate
synthetase. The involvement of the DNA-binding proteins PepA and
IHF in this process is indicated. Figure 1. Pyrimidine
nucleotide biosynthesis and the roles of UMPK demonstrated in
Escherichia coli. Prokaryotic UMPK is highlighted within a grey
box. The eukaryotic CMP/UMPK is included also. Multiple arrows
denote multiple steps. The broken and dotted arrows denote
feed-back inhibition and activation, respectively. The
double-lined arrow indicates repression by UMPK of the carAB
genes, which encode carbamoyl phosphate synthetase. The
involvement of the DNA-binding proteins PepA and IHF in this
process is indicated.
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