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Figure 1.
Figure 1. Solution Structure of CyaY and Comparison with
the Crystal Structure and the Human Ortholog(A) A set of 20
energy-minimized conformers of bacterial frataxin CyaY
superposed on the average structure (shown in red).(B) Average
NMR structure showing the N- and C-terminal a helices packed
against a six-stranded b sheet. The N and C termini are also
indicated.(C) Pairwise superposition of the corresponding NMR
(in green) and crystallographic (1ew4, in blue) structures of
CyaY is shown.(D) Structural comparison of the NMR (1ly7, in
green) and the crystal (1dlx, in green) structures of
hfra(91-210) (in blue) using the same orientation as in (C).
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