Figure 1 - full size

 

Figure 1.
Figure 1. Structural model of protein Y binding to the ribosome as determined by X-ray crystallography. (a) Location of PY density in the 70S ribosome. The 30S subunit is gold, the 50S subunit is light blue, positive difference electron density is blue, negative density is red, and PY is cyan. Helix 69 of 23S rRNA is marked with an asterisk. (b) PY density in the 30S subunit as seen from the perspective of the subunit interface, indicated by the arrow in a. The density occurs between the platform (P) and the head (H) of the 30S subunit. The A, P and E sites, and the body (B) of the small subunit are marked. (c) Details of the docking of the N-terminal core of PY (PDB entry 1L4S 3) into the difference electron density. The position of the disordered C-terminal tail is indicated. The view is from the perspective of the arrow in b.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Mol Biol (2004, 11, 1054-1059) copyright 2004.