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Figure 1.
Figure 1. Structure of the ABAD/HSD10 monomer. (a) Stereo
C^a trace of ABAD/HSD10 monomer. Every tenth residue is
numbered. The bound NAD-inhibitor adduct is shown. (b) Ribbon
diagram of ABAD/HSD10 monomer, with the NAD-inhibitor adduct
shown in ball-and-stick representation. The ribbon is white at
the amino terminus and becomes darker blue moving toward the
carboxy terminus. C^a positions of residues in the insertion
regions of ABAD/HSD10 relative to other SDR enzymes (residues
102-107 and 141-146, see Figure 2) are shown as yellow spheres.
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