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Figure 1.
Figure 1. Structure of E. coli YddE. (A) View of the dimer with
the two separate domains from each subunit shown in blue and
yellow. (B) Ribbon diagram of the molecule colored as in (A) and
viewed perpendicular to the internal approximate 2-fold axis.
The secondary structure elements are indicated. (C) Molecular
surface representation of the molecule oriented 90° from
(B). The large cleft at the domain interface is visible (center)
with Cys72 indicated in red. (D) Close view of the predicted
catalytic site with side-chains shown through a transparent
surface and colored blue for domain 1 and yellow for domain 2.
The glycerol molecule is shown in orange. (E) Ribbon diagram of
DAP epimerase (accession number 1BWZ) oriented and colored as in
(B). The regions that significantly differ from YddE are between
DAP epimerase and YddE are indicated in orange.
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