Figure 1 - full size

Figure 1. FIG. 1. Biosynthetic pathway leading to clavulanic acid. BLS, -lactam synthetase; PAH, proclavaminate amidino hydrolase; CAS, clavaminic synthase; CAD, clavaldehyde dehydrogenase; 2-OG, 2-oxoglutarate.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2004, 279, 5685-5692) copyright 2004.