Figure 1 - full size

 

Figure 1.
FIG. 1. Stereographic projection of the active site of GABA-AT. The final model is shown together with the 2F[o] - F[c] map (contour level, 1.2 ). An acetate molecule is found close to Arg-192, i.e. at a position where the carboxylate moiety of the natural substrate GABA is expected to bind (6).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2004, 279, 363-373) copyright 2004.