Figure 1.
FIG. 1. Stereographic projection of the active site of
GABA-AT. The final model is shown together with the 2F[o] - F[c]
map (contour level, 1.2 ). An acetate molecule
is found close to Arg-192, i.e. at a position where the
carboxylate moiety of the natural substrate GABA is expected to
bind (6).
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2004,
279,
363-373)
copyright 2004.