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Figure 1.
Figure 1. Stereo view of the quarternary assembly of
isoaspartyl dipeptidase (IadA). (a) The octamer can be regarded
as a tetramer of dimers with the indicated 422 symmetry. The
nomenclature of the monomers as well as the location of the
active site zincs (magenta spheres) are given. The monomers in
the foreground are colored in light green (A), orange (B), green
(C), and blue (D), the monomers in the background are colored in
gray. Dimers are formed between molecules A-E, B-F, C-G and D-H,
respectively. (b) Surface of isoaspartyl dipeptidase. The
electrostatic potential was calculated with GRASP,[48.] using
charges according to Weiner and co-workers. [50.]
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