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Figure 1.
Figure 1. Structure of PSD-95 PDZ1 determined by NMR
spectroscopy. (A) Stereoview showing the best-fit superposition
of the backbone atoms (N, C^a, and C') of the final 20
structures of PSD-95 PDZ1. The structures are superimposed
against the average structure using the residues 64-148. The
structural statistics are summarized in Table 1. (B) Ribbon
diagram presentation of PSD-95 PDZ1. The secondary structure
elements are labelled following the scheme used in the crystal
structure of PSD-95 PDZ3. [7] (C) Comparison of the 3D
structures of PDZ1 and PDZ2 of PSD-95. The backbone traces (N,
C^a, and C') of PDZ1 (gold) and PDZ2 (yellow) are superimposed.
The two structures were fit to each other by excluding the
GLGF-loop, bB/bC loop and the two termini. The rmsd between the
backbones of the two PDZ domains is 1.35 Å.
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