Figure 1 - full size

 

Figure 1.
Fig. 1. Classical acid/base mechanism for RNase-catalyzed phosphoryl transfer reactions. AH and B represent the catalytic acid and base respectively; bent arrows represent the movement of electrons.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2002, 277, 36770-36774) copyright 2002.