Figure 1 - full size

 

Figure 1.
Figure 1. A: Ribbon diagram of a subunit of MTH1020. The protein is composed of a single domain with an - - core. The secondary structure elements are numbered. B: Structure superposition of MTH1020 (green) with a member of the NTN-hydrolase family (blue) showing the similarity of the structure of MTH1020 with NTN-hydrolases. The arrows depict Arg5 and the N-terminal nucleophile of the NTN-hydrolase member in ball and stick form showing the similarity in position of Arg5 with the N-terminal nucleophile. The programs MOLSCRIPT and RASTER 3D were used in the production of the figures.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2002, 48, 141-143) copyright 2002.