Figure 1 - full size

 

Figure 1.
Fig. 1. (a) Global view of the transmembrane helical region of the refined bovine rhodopsin structure. The cytoplasmic surface is shown in the upper side. The four water-binding sites (Wat1-4) include seven water molecules (light blue spheres). Details of the sites are summarized in Table 2. (b) Detailed view of the Wat1 site. The residues surrounding Wat1a, -b, and -c are shown as ball-and-stick representation in standard atom colors. Colors of the stick are yellow for the conserved residues, cyan for Ala-124, and green for Phe-261. Numbers in parentheses are according to ref. 18. Figures were prepared with MOLSCRIPT (38) and RASTER3D (39).