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Figure 1.
Figure 1. Structure of the KB5-C20/pKB1/H-2K^b
ComplexBackbone ribbon representation of the ternary complex
showing the overall orientation of the KB5-C20 scFv TCR onto
pKB1 bound to the H-2K^b MHC molecule. Domains are color coded
as follows: TCR Vα, light red; TCR Vβ, light blue; H-2K^b α1
domain, green; H-2K^b α2 domain, light purple; H-2K^b α3
domain, pink; β2-microglobulin, dark purple. The CDR1 and CDR2
loops from both V domains are drawn as green and red coils,
respectively. CDR3α is depicted in dark blue, and CDR3β in
light blue. The pKB1 is shown in yellow and in a ball-and-stick
format, with the N-terminal end on the left and C-terminal end
on the right. Only one of the two complexes in the asymmetric
unit of the crystal is shown. Also shown is the carbohydrate
chain that could be modeled at the Asn^21α glycosylation site.
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