Figure 1.
Fig. 1. Mechanism of the acetyltransferase reaction
catalyzed by AANAT (A) and alkyl transfer between CoASH and
N-bromoacetyltryptamine (compound 1), resulting in the
bisubstrate analog inhibitor (compound 2) (B).
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2002,
277,
18118-18126)
copyright 2002.