Figure 1.
Fig. 1. 2mF[o] DF[c]
electron density for the TRPSIAAA structures at the -active
site. The density is shown at 1 -contouring
for the IAAA molecule, Glu49, Asp60, Thr183, and
for water molecules, which form hydrogen bonds with the -ligand.
The hydrogen bonds of the enzymatic important amino acids Glu49 and
Asp60 are
shown as dashed lines (see Table II). The figure was prepared
using "BOBSCRIPT" (40), "MOLSCRIPT" (41), and "RASTER3D" (42,
43). A, TRPSIAD structure. B, TRPSIAG structure. The second
conformation of Glu49 is
shown in orange. C, TRPSIAV structure.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2002,
277,
10647-10652)
copyright 2002.
DF[c]
electron density for the TRPSIAAA structures at the 
-active
site. The density is shown at 1 
-contouring
for the IAAA molecule,