Figure 1 - full size

 

Figure 1.
Fig. 1. a, stereo representation of the superposition of the GABARAP and GATE-16 main chains. b, cartoon diagram of the GABARAP three-dimensional backbone structure. Region 1-35 is in green, region 35-68 is in red, and region 68-117 is in blue. Therefore, the baits used in the two hybrids are the 35-117 region (colored in red and blue) and the 1-68 region (colored in green and red). c, backbone trace of GABARAP in the same orientation as b, showing residues discussed in the text. Conserved residues are shown in red for acidic residues, blue for basic residues, magenta for polar residues, green for residues involved in turns, and black for hydrophobic core residues. The nonconserved Phe^3 is shown in light gray, and water molecules involved in the region of the salt bridges are shown in cyan. This figure was prepared with MOLSCRIPT (32) and RASTER3D (33).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2002, 277, 5556-5561) copyright 2002.