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Figure 1.
Figure 1. Crystal structure of the stromelysin-3 catalytic
domain complexed with the phosphinic inhibitor. (a) Ribbon
diagram showing the catalytic domain of ST3 (blue), the
phosphinic inhibitor (pink), the two zinc atoms (red spheres)
and the calcium atom (blue sphere). The Figure was created with
Setor.[45] (b) The molecular surface of the ST3 catalytic domain
is coloured according to its potential (red: negatively charged
residues; blue, positively charged residues). The catalytic zinc
atom (green) lies on the surface of the active site. The Figure
was created with GRASP. [46]
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