Figure 1 - full size

Figure 1. Figure 1. (a) Electron density for the bound peptide in the HLA-DR2a/MBP 86-105 complex. The Fo - Fc omit map at 1.9 Å resolution is contoured at 2s. (b) Superposition of the MBP 86-105 peptide (red) bound by HLA-DR2a onto the MBP 85-99 peptide (green) bound by HLA-DR2b (Smith et al., 1998). (c) Alignment of MBP 86-105 and MBP 85- 99 according to their registers in the peptide-binding grooves of HLA-DR2a and HLA-DR2b, respectively.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2000, 304, 177-188) copyright 2000.