Figure 1 - full size

 

Figure 1.
Fig. 1. Crystal structure of the AR·Adx complex. AR-Adx contacts occur at the primary and secondary interaction regions and the region between the [2Fe-2S] cluster of Adx and the isoalloxazine ring of the FAD of AR. C-terminal residues of Adx are also in contact with AR. The side chains of some residues involved in polar AR-Adx interactions are displayed. For close-ups of the contact sites see Figs. 3 and 4. The brown triangle marks the position of Adx Lys66 and the green marks AR Glu4, both residues maintaining another cross-link reported recently (11, 12). Figure was produced with MOLSCRIPT (17).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2001, 276, 2786-2789) copyright 2001.